The first reports of iPS cells were in 2006 (mouse) and 2007 (human). It includes recommended resources about them. We stained them in red for a human embryonic stem cell marker. You can see a microscopy image of colonies of human IPS cells that my lab produced years ago. We’ve been doing iPS cell research ourselves in the Knoepfler lab for more than a dozen years. You might have noticed that here on The Niche we have the URL . So when it comes to induced pluripotent stem cells, we know our stuff. At The Niche, we do our own IPS cell research He applied basic science knowledge gained over many years about embryonic stem cells and transcription factors.īut the story leading up to iPS cells really starts in the 1980s in part in Seattle. Shinya Yamanaka, received the Nobel Prize in 2012 for this discovery.
This may manifest both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as drug screening.
They have unique potential for clinical impact for regenerative medicine too. IPS cells, induced pluripotent stem cells, Knoepfler lab, stained for TRA-1-60, an ES cell marker. Induced pluripotent stem cells or iPS cells just might be the most exciting development in the stem cell field over the last 15 years.
